application of phase transfer catalyst for synthesizing of 5, 5-diphenylimidazolidine-2,4-dione as a famous anticonvulsant drug

نویسندگان

abbas ahmadi

babak nahri-niknafs

mohammad hadi riahi

چکیده

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Application of Phase Transfer Catalyst for Synthesizing of 5, 5-diphenylimidazolidine-2,4-dione as a Famous Anticonvulsant Drug

Epilepsy is a major neurological disorder in the world and most epileptics are currently controlled by a variety of drugs. 5, 5-diphenylimidazolidine-2,4-dione (Phenytoin, I) is a widely used antiepileptic drug. It has been synthesized previously by different methods in some solvents. In this work, I was synthesized from the condensation of benzil and urea in ethanol and water by application of...

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The interaction of the perimidone drug in solution state with the σ-acceptor iodine, the aliphatic π-acceptor tetracyanoethylene (TCNE) and the aromatic π-acceptor 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) have been studied through the initial formation of ionic intermediate to charge transfer (CT) complex in methanol at room temperature. The spectral studies of the complexes were determi...

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عنوان ژورنال:
quarterly journal of applied chemical research

ناشر: islamic azad university, karaj branch

ISSN 2008-3815

دوره 8

شماره 1 2014

کلمات کلیدی

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